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Prevention of CVD, Hypertension, Smoking, Diabetes and High Cholesterol

Prevention of Cardio-Vascular disease (CVD)

Prevention of Cardio-Vascular disease (CVD) CVD is a major public health problem. CVD prevention can help keep people’s hearts healthy and prevent strokes. The best way to prevent cardiovascular disease is for people to eat better and be more active. “ An estimated 2.8 million men and 2.8 million women in the UK are living with CVD. The British Heart Foundation estimates that around 111,000 people have a stroke for the first time every year.” CVD includes coronary heart disease (CHD), stroke and peripheral arterial disease. These conditions are frequently brought about by the development of blockages in the arteries. They are also linked to conditions such as heart failure, chronic kidney disease and dementia. Cardiovascular disease (CVD) is generally due to reduced blood flow to the heart, brain or body. It is increasingly common after the age of 60, but rare below the age of 30. Some countries have much more cardiovascular disease than others and, unfortunately, the UK sits at the top of the table – just like the average cholesterol levels. In England in 2007, CVD led to nearly 159,000 deaths (accounting for nearly 34% of all deaths in England). Most premature deaths from CVD – that is, among people aged less than 75 – are preventable. An estimated 2.8 million men and 2.8 million women in the UK are living with CVD. The British Heart Foundation estimates that around 111,000 people have a stroke for the first time every year. Despite recent improvements, death rates in the UK from CVD are relatively high compared with other developed countries (only Ireland and Finland have higher rates). Stop smoking, eat healthier foods, increase aerobic physical activity, and achieve optimal weight and weight distribution are central to CVD prevention. Modifiable Risk Factors In more than 90% of cases, the risk of a first heart attack is related to nine potentially modifiable risk factors (Yusuf et al. 2004): • Smoking/tobacco use • Poor diet • High blood cholesterol • High blood pressure • Insufficient physical activity • Overweight/obesity • Diabetes • Psychosocial stress • Excess alcohol consumption. Smoking, obesity and a physically inactive lifestyle are among the top risk factors for developing Coronary Heart Disease (CHD). In 2007, over 20,000 deaths from cardiovascular disease in England were related to smoking. That’s why the NSF has driven forward major developments in prevention. Stroke A stroke is a serious medical condition that occurs when the blood supply to part of the brain is cut off. There are two main types of stroke. The most common type (an ischaemic stroke) is when one of the blood vessels leading to or in the brain is blocked. The second type (haemorrhagic stroke) is when a blood vessel in the brain bursts, causing bleeding into the brain. A transient ischaemic attack (TIA), often called a ‘mini- stroke’, happens when the blood supply to part of the brain is interrupted for a short time. The symptoms are the same as for a stroke, but they usually last only a few minutes or hours, and disappear altogether within 24 hours. Causes of stroke Stroke is a largely preventable condition. Many of the key risk factors such as smoking, high blood pressure, obesity and high cholesterol levels can be reduced by making lifestyle changes. There are some risk factors for stroke that cannot be changed, including: • age (higher risk if you are over 65) • family history • ethnicity (higher risk in south Asian, African and Caribbean) • your medical history (previous stroke, TIA or heart attack) Cutting the risk Strokes can usually be successfully treated and also prevented. Eating a healthy diet, taking regular exercise, drinking alcohol in moderation and not smoking will dramatically reduce your risk of having a stroke. Lowering high blood pressure and cholesterol levels with medication also lowers the risk of stroke substantially. Reducing the risks can rapidly reduce the likelihood of developing CVD. Diet A poor diet is a major risk factor for a stroke. High-fat foods can lead to the build-up of fatty plaques in your arteries and being overweight can lead to high blood pressure. A low-fat, high-fibre diet is recommended, including plenty of fresh fruit and vegetables (five portions a day)and whole grains. Salt intake is a major determinant of CVD in the UK, mainly due to its effect on blood pressure. On average, 70%–90% of people’s intake comes from salt added during the manufacturing process; only 10–30% comes from adding it during cooking or at the table. You should limit the amount of salt that you eat to no more than 6g (0.2oz) a day because too much salt will increase your blood pressure. Six grams of salt is about one teaspoonful. Lifestyle targets 1. Do not smoke 2. Maintain ideal body weight for adults (body mass index 20– 25 kg/m2) and avoid central obesity (waist circumference in white Caucasians 102 cm in men and 88 cm in women, and in Asians 90 cm in men and 80 cm in women) 3. Keep total dietary intake of fat to 30% of total energy intake 4. Keep the intake of saturated fats to 10% of total fat intake 5. Keep the intake of dietary cholesterol to 300 mg/ day 6. Replace saturated fats by an increased intake of monounsaturated fats 7. Increase the intake of fresh fruit and vegetables to at least five portions per day 8. Regular intake of fish and other sources of omega 3 fatty acids (at least two servings of fish per week) 9. Limit alcohol intake to 21 units per week for men or 14 units per week for women 10. Limit the intake of salt 11. Regular aerobic physical activity of at least 30 mins per day, most days of the week, should be taken (for example, fast walking/swimming) Source Joint British Societies’ Guidelines Exercise Combining a healthy diet with regular exercise is the best way to maintain a healthy weight. Having a healthy weight reduces your chances of developing high blood pressure. Regular exercise will make your heart and blood circulatory system more efficient. It will also lower your cholesterol level and keep your blood pressure at a healthy level. Regular exercise can help you lose weight. For most people, 30 minutes of vigorous exercise a day at least five times a week is recommended. The exercise should be strenuous enough to leave your heart beating faster, and you should feel slightly out of breath. Examples of vigorous exercise are going for a brisk walk or walking up a hill. Want to know more? www.nhs.uk/LiveWell/Fitness/Pages/Fitnesshome. aspx Smoking Smoking doubles your risk of having a stroke. This is because it narrows your arteries and makes your blood more likely to clot. If you stop smoking, you can reduce your risk of having a stroke by up to half. Not smoking will also improve your general health and reduce your risk of developing other serious conditions, such as lung cancer and heart disease. The NHS Smoking Helpline can offer advice and encouragement to help you quit smoking. You can call on 0800 022 4332, or visit http://smokefree.nhs.uk Want to know more? www.nhs.uk/LiveWell/Smoking/Pages/stopsmokin gnewhome.aspx Alcohol Excessive alcohol consumption can lead to high blood pressure and an irregular heartbeat (atrial fibrillation).Both are major risk factors for stroke. Because alcoholic drinks are rich in energy (high incalories) they also cause weight gain. Heavy drinking multiplies the risk of stroke by more than three times. Want to know more? www.nhs.uk/LiveWell/Alcohol/Pages/Alcoholhom e.aspx Treatment Individuals at high cardiovascular risk warrant intervention with lifestyle changes and consideration for drug therapy, to reduce their absolute risk. Whether or not surgery is needed, anyone with narrowing of the carotid artery should be given antiplatelet drugs to reduce blood clotting. They should also be offered advice and/or medication for controlling blood pressure and reducing cholesterol (NICE Clinical Guidance 68). Antiplatelet medicines reduce the risk of clots forming in the blood. This reduces your risk of having a stroke or heart attack. Low-dose aspirin (usually 75mg a day) may be given to you if you are considered to be at risk of having a heart attack or stroke. You may be considered to be at risk if you: • have high cholesterol • have high blood pressure • have diabetes • smoke Scottish National Clinical Guidance recommends asymptomatic individuals without established atherosclerotic disease but with a calculated cardiovascular risk of >20% over ten years should be considered for treatment with aspirin 75 mg daily. However, Low-dose aspirin should not be taken if you have: • an active (bleeding) peptic ulcer • haemophilia or any other bleeding disorder • an allergy to aspirin or to non-steroidal anti- inflammatory drugs (NSAIDs) such as ibuprofen or diclofenac All adults over the age of 40 years who are assessed as having a ten year risk of having a first cardiovascular event >20% should be considered for treatment with simvastatin 40 mg/day following an informed discussion of risks and benefits between the individual and responsible clinician. For patients who face many years of risk after diagnosis of a significant carotid narrowing (with or without symptoms), early surgery called a carotid endarterectomy to remove the blockage is the most important and effective intervention to reduce still further the risk of stroke. For more information visit: Stroke Association, 0845 3033 100, www.stroke.org.uk Northern Ireland Chest, Heart and Stroke Association, 0845 7697 299, www.nichsa.com Different Strokes, 0845 130 7172, www.differentstrokes.co.uk http://www.nhs.uk/NHSEngland/NSF/Pages/Coro naryheartdisease.aspx http://guidance.nice.org.uk/CG68
Having an excessively high level of lipids in your blood (hyperlipidaemia) can have a serious effect on your health as it increases your risk of having a heart attack or stroke. Bad Cholesterol (LDL - low density lipoprotein) accounts for 70% of the cholesterol in our blood and acts to carry cholesterol from your liver to the cells that need it. If there is too much cholesterol for the cells to use, this can cause a harmful build-up in your blood. Good Cholesterol (HDL - high density lipoprotein) carries cholesterol away from the cells and back to the liver for excretion from the body via the gastro-intestinal system. There it is either broken down or passed from the body as a waste product. If your HDL levels are low and your total cholesterol is normal or above then your chances of a heart attack are higher. Your body needs cholesterol to: • make up the structure of the membrane (outer layer) of every cell in the body • insulate nerve fibres • make hormones, such as sex hormones and steroid hormones • make bile acids, which are needed for the digestion and absorption of fats Triglycerides are the fats you use for energy and come from the fatty foods you eat. There is usually an association between triglycerides and raised cholesterol. Being overweight and drinking too much alcohol can push up triglyceride levels. The optimal total cholesterol target is 4.0 mmol/l and low density lipoprotein (LDL) cholesterol 2.0 mmol/l, or a 25% reduction in total cholesterol and a 30% reduction in LDL cholesterol, whichever gets the person to the lowest absolute value. The government recommends that minimum standards of cholesterol levels should be less than 5.0 mmol/l. In the UK, two out of three adults have a total cholesterol level of 5.0 mmol/l or above. Risks of high cholesterol High cholesterol is not a disease but increases your risk of serious conditions such as: • coronary heart disease, caused by atherosclerosis (narrowing of the arteries) • stroke • mini-stroke (transient ischaemic attack or TIA) “The UK population has one of the highest average cholesterol concentrations in the world.” A number of different factors can contribute to high blood cholesterol, including: • Lifestyle factors: unhealthy diet, lack of exercise or physical activity, obesity and drinking excessive amounts of alcohol • Treatable factors: hypertension, diabetes and underactive thyroid gland • Fixed factors: family history of early heart disease, stroke or cholesterol-related condition; age, ethnic group Who should be tested? Anyone can have their blood cholesterol level tested, but it is particularly important to have it checked if: • You have been diagnosed with coronary heart disease, suffered a stroke/mini-stroke or you have leg artery disease • You are over 40 • You have a family history of early cardiovascular disease (for example, if your father or brother developed heart disease or had a heart attack or stroke before the age of 55, or if your mother or sister had these conditions before the age of 65) • A close family member has a cholesterol-related condition, such as familial hypercholesterolaemia (inherited high cholesterol) • You are overweight or obese • You have high blood pressure or diabetes • You have another medical condition such as a kidney condition, an underactive thyroid gland or an inflamed pancreas (pancreatitis). These conditions can cause increased levels of cholesterol or triglycerides Treating high cholesterol If you have been diagnosed with high cholesterol, the first method of treatment will usually involve making some changes to your diet (adopting a low-fat diet) and doing plenty of regular exercise. After a few months, if your cholesterol level has not dropped, you will usually be advised to take cholesterol-lowering medication. A healthy diet includes foods from all of the different food groups: • Carbohydrates (cereals, wholegrain bread, potatoes, rice and pasta) • Proteins (lean meat, beans and fish) • Unsaturated fats • Fruit and vegetables (at least five portions a day) You should try to avoid or cut down on the following foods, which are rich in saturated fat: • Fatty cuts of meat and meat products, such as sausages and pies • Butter, ghee and lard • Cream, soured cream, creme fraiche and ice cream • Cheese, particularly hard cheese • Cakes and biscuits • Chocolate • Coconut oil, coconut cream and palm oil Switching saturated fats to mono-unsaturated fats such as olive oil can actually lower total cholesterol whilst preserving the important HDL cholesterol. We also know that the vitamin Niacin can help toreduce cholesterol. It is virtually impossible to develop coronary heart disease if your cholesterol level is below 3.8 mmol/l. Studies overwhelmingly show that it is perfectly possible to stop and even to reverse the build up of fatty deposits within artery walls. You can help prevent getting high blood cholesterol by eating a healthy, balanced diet that is low in saturated fat. For more information visit: www.nhs.uk/conditions/Cholesterol/Pages/Introductio n.aspx www.nhs.uk/LiveWell/healthy- eating/Pages/Healthyeating.aspx www.nhs.uk/LiveWell/Loseweight/Pages/Loseweight home.aspx

Hypertension (High blood Pressure)

High blood pressure is usually defined as having a sustained blood pressure of 140/90mmHg or above. As hypertension often causes no symptoms, or immediate problems, it is known as the ‘silent killer’. However, it is a major primary risk factor in the development of coronary heart disease, stroke and kidney failure. The only way to find out whether you have high blood pressure is to have it checked regularly. “High blood pressure is a common condition, affecting around one in three adults in England. The risk of developing high blood pressure increases with age. Half of people over 75 years have the condition.” If you have high blood pressure, your heart has to work harder to pump blood around your body. Over time, this can weaken it. The increased pressure can also damage the walls of your arteries, resulting in a blockage or causing the artery to split (haemorrhage). Both of these situations can cause a stroke. High blood pressure is a common condition, affecting around one in three adults in England. It is estimated that 18% of adult men and 13% of adult women have high blood pressure but are not getting treatment for it. The risk of developing high blood pressure increases with age. Half of people over 75 years have the condition. There are two types of high blood pressure: Primary high blood pressure (90-95% of cases), there is no identifiable cause for this type of high blood pressure. A number of risk factors increase your chances of developing the condition including: • age - the risk of developing high blood pressure increases as you get older • a family history of high blood pressure – the condition seems to run in families • being of Afro-Caribbean origin • high-fat diet • high amount of salt in your diet • lack of exercise • being overweight • smoking • excessive alcohol consumption • stress All available evidence shows that lifestyle plays a significant role in regulating your blood pressure. Secondary high blood pressure (between 5 and 10%), where high blood pressure is caused by an underlying cause, such as kidney disease, or a particular type of medication that you are taking. High blood pressure can be treated or prevented by making changes to your lifestyle, such as eating a healthier diet, exercising more regularly, and reducing the amount of alcohol you drink. Blood pressure is measured using two figures. One figure represents the pressure of the heart as it contracts to pumps blood around the body. This is known as the systolic pressure. The second figure represents the pressure of the heart as it expands and fills with blood, while waiting for the next contraction. This is known as the diastolic pressure. “All available evidence shows that lifestyle plays a significant role in regulating your blood pressure.” It is important to recognise that blood pressure will vary dependent upon many situational factors. Physical activity, emotion, hydration, smoking, caffeine and time of day are just some of the factors that can significantly impact blood pressure immediately. For most people, a healthy blood pressure is a systolic pressure of 90-120 millimeters of mercury (mmHg) and a diastolic pressure of 60- 80mmHg. Or, as blood pressure is normally expressed, a level between 90/60mmHg and 120/80mmHg. Checking your blood pressure Having one high blood pressure reading does not necessarily mean that you have high blood pressure. Your blood pressure can fluctuate throughout the day. Therefore, your GP will need to take several readings over a set period of time, usually every month, to see whether your blood pressure level is consistently high. “Having one high blood pressure reading does not necessarily mean that you have high blood pressure.” Before having your blood pressure taken, you should rest for at least five minutes and empty your bladder. To get an accurate blood pressure reading, you should be sitting down and not talking when the reading is taken. The optimal BP target is 140 mm Hg systolic and 85 mm Hg diastolic higher risk people (established atherosclerotic disease, diabetes, and chronic renal failure) a lower BP target of 130 mm Hg and 80 mm Hg. The best way of preventing high blood pressure and the associated risks of cardiovascular disease, is to eat a healthy diet, maintain a healthy weight, exercise regularly, drink alcohol in moderation and avoid smoking. Treating high blood pressure Treatment for high blood pressure will depend on your blood pressure levels and your associated risk of developing a cardiovascular disease, such as a heart attack or stroke. Slightly High blood Pressure If your blood pressure is slightly higher than the ideal level (120/80mmHg), and your GP feels that the risks of cardiovascular disease are low, you should be able to lower your blood pressure by making simple lifestyle changes, such as improving your diet and taking regular exercise. moderately High blood Pressure If your blood pressure is moderately high (140/90mmHg or higher), or your GP feels that your risk of developing cardiovascular disease in the next 10 years is more than one in five, you will be prescribed medication and advised about changing your lifestyle. Very High blood Pressure If your blood pressure is very high (180/110 mmHg or above) you will be referred to a hypertension specialist (a doctor who specialises in treating high blood pressure). For more information visit: www.nhs.uk/conditions/Blood-pressure- (high)/Pages/Introduction.aspx http://guidance.nice.org.uk/CG127

HIGH CHOLESTEROL

Having an excessively high level of lipids in your blood (hyperlipidaemia) can have a serious effect on your health as it increases your risk of having a heart attack or stroke. Bad Cholesterol (LDL - low density lipoprotein) accounts for 70% of the cholesterol in our blood and acts to carry cholesterol from your liver to the cells that need it. If there is too much cholesterol for the cells to use, this can cause a harmful build-up in your blood. Good Cholesterol (HDL - high density lipoprotein) carries cholesterol away from the cells and back to the liver for excretion from the body via the gastro-intestinal system. There it is either broken down or passed from the body as a waste product. If your HDL levels are low and your total cholesterol is normal or above then your chances of a heart attack are higher. Your body needs cholesterol to: • make up the structure of the membrane (outer layer) of every cell in the body • insulate nerve fibres • make hormones, such as sex hormones and steroid hormones • make bile acids, which are needed for the digestion and absorption of fats Triglycerides are the fats you use for energy and come from the fatty foods you eat. There is usually an association between triglycerides and raised cholesterol. Being overweight and drinking too much alcohol can push up triglyceride levels. The optimal total cholesterol target is 4.0 mmol/l and low density lipoprotein (LDL) cholesterol 2.0 mmol/l, or a 25% reduction in total cholesterol and a 30% reduction in LDL cholesterol, whichever gets the person to the lowest absolute value. The government recommends that minimum standards of cholesterol levels should be less than 5.0 mmol/l. In the UK, two out of three adults have a total cholesterol level of 5.0 mmol/l or above. Risks of high cholesterol High cholesterol is not a disease but increases your risk of serious conditions such as: • coronary heart disease, caused by atherosclerosis (narrowing of the arteries) • stroke • mini-stroke (transient ischaemic attack or TIA) “The UK population has one of the highest average cholesterol concentrations in the world.” A number of different factors can contribute to high blood cholesterol, including: • Lifestyle factors: unhealthy diet, lack of exercise or physical activity, obesity and drinking excessive amounts of alcohol • Treatable factors: hypertension, diabetes and underactive thyroid gland • Fixed factors: family history of early heart disease, stroke or cholesterol-related condition; age, ethnic group Who should be tested? Anyone can have their blood cholesterol level tested, but it is particularly important to have it checked if: • You have been diagnosed with coronary heart disease, suffered a stroke/mini-stroke or you have leg artery disease • You are over 40 • You have a family history of early cardiovascular disease (for example, if your father or brother developed heart disease or had a heart attack or stroke before the age of 55, or if your mother or sister had these conditions before the age of 65) • A close family member has a cholesterol-related condition, such as familial hypercholesterolaemia (inherited high cholesterol) • You are overweight or obese • You have high blood pressure or diabetes • You have another medical condition such as a kidney condition, an underactive thyroid gland or an inflamed pancreas (pancreatitis). These conditions can cause increased levels of cholesterol or triglycerides Treating high cholesterol If you have been diagnosed with high cholesterol, the first method of treatment will usually involve making some changes to your diet (adopting a low-fat diet) and doing plenty of regular exercise. After a few months, if your cholesterol level has not dropped, you will usually be advised to take cholesterol-lowering medication. A healthy diet includes foods from all of the different food groups: • Carbohydrates (cereals, wholegrain bread, potatoes, rice and pasta) • Proteins (lean meat, beans and fish) • Unsaturated fats • Fruit and vegetables (at least five portions a day) You should try to avoid or cut down on the following foods, which are rich in saturated fat: • Fatty cuts of meat and meat products, such as sausages and pies • Butter, ghee and lard • Cream, soured cream, creme fraiche and ice cream • Cheese, particularly hard cheese • Cakes and biscuits • Chocolate • Coconut oil, coconut cream and palm oil Switching saturated fats to mono-unsaturated fats such as olive oil can actually lower total cholesterol whilst preserving the important HDL cholesterol. We also know that the vitamin Niacin can help toreduce cholesterol. It is virtually impossible to develop coronary heart disease if your cholesterol level is below 3.8 mmol/l. Studies overwhelmingly show that it is perfectly possible to stop and even to reverse the build up of fatty deposits within artery walls. You can help prevent getting high blood cholesterol by eating a healthy, balanced diet that is low in saturated fat. For more information visit: www.nhs.uk/conditions/Cholesterol/Pages/Introductio n.aspx www.nhs.uk/LiveWell/healthy- eating/Pages/Healthyeating.aspx www.nhs.uk/LiveWell/Loseweight/Pages/Loseweight home.aspx

Smoking

If you smoke, giving up is probably the greatest single step you can take to improve your health. Stopping smoking can be followed by a rapid decline in the risk of CHD. Smoking’s impact on public health is huge. Smoking is responsible for one in every five deaths in adults aged over 35 in England, and half of all long-term smokers will die prematurely due to a smoking-related disease. Smoking and Stroke In asymptomatic people, up to 10 years are needed to reach the risk level of those people who have never smoked. Smoking doubles your risk of having a stroke.This is because it narrows your arteries and makes your blood more likely to clot. Approximately 100,000 people die from smoking- related diseases in the UK every year. Tobacco accounts for approximately 29% of deaths from cancer, 13% of cardiovascular deaths and 30% of deaths from respiratory disease. Tobacco smoke contains nicotine, which is highly addictive. As well as nicotine, each cigarette contains more than 4,000 different chemicals, many of which are toxic (harmful to the body). More than 60 of them cause cancer (are carcinogenic). Some of the most harmful conditions that smoking can cause are: 1. Premature death 2. Cancer 3. Respiratory diseases 4. Cardiovascular and cerebrovascular diseases 5. Osteoporosis, stomach ulcers and infertility Risks to others When you smoke, it is not just your health that is at risk, but the health of anyone who breathes in cigarette smoke (including those around you). The smoker only inhales about 15% of the smoke from a cigarette. The other 85% is absorbed into the atmosphere or inhaled by other people who are passive smokers. “Stopping smoking can be followed by a rapid decline in the risk of CHD.” Around 65% of smokers say they want to stop smoking, but most believe they are unable to. However, around half of all smokers eventually manage to give up. When you stop smoking, the benefits to your health begin straight away. It is generally a good idea to fix a quit date, rather than gradually reduce your smoking. Tell people around you that you are going to stop, and try to get others at home or work to stop with you. This support network makes it easier when temptation arises! Be prepared to fail and try again Please don’t despair if you fail on your first attempt! You won’t be the first or last smoker that this has happened to. Regroup, work out what went wrong - was it peer pressure, alcohol, stress, etc? Don’t be ashamed and it is very important at this stage to maintain your nicotine replacement therapy, family and group support. Try Again! The NHS Smoking Helpline can offer advice and encouragement to help you quit smoking. You can call on 0800 022 4332, or visit NHS

Diabetes

It is important to diagnose diabetes as early as possible so that treatment can be started. In the presence of diabetic symptoms (thirst, polyuria, and weight loss) a fasting glucose of > 7 mmol/l or Random > 11.1 mmol/l on one occasion is considered diagnostic of diabetes. If there are 2 fasting glucose values > 7.0 mmol/l or 2 random > 11.1 mmol/l on 2 separate occasions, the diagnosis of diabetes is made regardless of symptoms. If your blood glucose levels are not high enough to diagnose diabetes, you may need to have an oral glucose tolerance test (OGTT). You will be given a glucose drink and then blood tests are taken every half an hour, for two hours, to see how your body is dealing with the glucose. In the UK, diabetes affects approximately 2.8 million people. More than one million people are thought to have undiagnosed type 2 diabetes. The main symptoms of undiagnosed diabetes can include: • passing urine more often than usual, especially at night (polyuria) • increased thirst • extreme tiredness • unexplained weight loss • genital itching or regular episodes of thrush • slow healing of cuts and wounds • blurred vision There are two main types of diabetes: Type 1 diabetes: symptoms can develop quickly, over weeks or even days. There is nothing that you can do to prevent Type 1 diabetes. This type of diabetes is always treated with insulin injections. Type 2 diabetes: occurs when not enough insulin is produced by the body for it to function properly, or when the body’s cells do not react to insulin. This is called insulin resistance. Type 2 diabetes is often associated with obesity. You should ask for a test for diabetes, if you: • are white and over 40 years old • are black, Asian or from a minority ethnic group and over 25 years old • have one or more of the following risk factors: • a close member of your family has Type 2 diabetes (parent or brother or sister). • you’re overweight or if your waist is 31.5 inches or over for women; 35 inches or over for Asian men and 37 inches or over for white and black men. • you’ve high blood pressure or you’ve had a heart attack or a stroke. “ In the UK, diabetes affects approximately 2.8 million people. More than one million people are thought to have undiagnosed type 2 diabetes.” Risk factors for type 2 diabetes You are more likely to develop type 2 diabetes if: • You have a relative with type 2 diabetes. • You are of South Asian, African-Caribbean or Middle Eastern descent. • You are overweight or obese. • You are over 40. • you’ve polycystic ovary syndrome and you are overweight. • you’ve been told you have impaired glucose tolerance or impaired fasting glycaemia. • if you’re a woman and you’ve had gestational diabetes. • you have severe mental health problems. “If your diabetes is not treated, it can lead to many different health problems. Large amounts of glucose can damage blood vessels, nerves and organs. If you have diabetes, you are up to five times more likely to have heart disease and a stroke than someone without diabetes.” All people with diabetes mellitus be considered ‘‘high risk’’ and managed to the same lifestyle and defined risk factor targets as people with established CVD and others at high total risk of developing CVD. This recommendation is made because most people with diabetes have a 10 year CVD risk > 20% and all have a risk greater than the population without diabetes. It may not be possible to avoid developing type 2 diabetes, but by controlling the risk factors you may be able to reduce your chances of getting it. For example, you should: • Lose weight, if you are overweight or obese • Keep your waist size under 31.5 inches (80cm) if you are a woman, 35 inches (90cm) if you are an Asian man and 37 inches (94cm) if you are a man who is white or black • Get at least 30 minutes of exercise every day • Do not smoke • Keep your blood pressure and cholesterol levels under control • Only drink alcohol in moderation This advice can help anyone reduce their risk of developing type 2 diabetes, but is particularly important for those who have an increased risk of developing it. For more information visit: www.diabetes.org.uk/ www.nice.org.uk/guidance/CG96 www.nhs.uk/LiveWell/Alcohol/Pages/Alcoholh ome.aspx www.nhs.uk/LiveWell/Loseweight/Pages/Lose weighthome.aspx www.nhs.uk/LiveWell/Fitness/Pages/Fitnessho me.aspx